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ARAF
Basic information
- Official gene symbol
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A-Raf proto-oncogene, serine/threonine kinase
- Conventional gene symbol
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A-RAF, ARAF1, PKS2, RAFA1
- Classification
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Oncogene
- Official gene ID
- Transcript ID
- Functional classification
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Tumor growth and progression
- Signaling pathway
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MAPK
- Chromosomal location
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Xp11.3 (chrX:47422367..47430856)
- Protein length
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606
Chromosome ideogram
Pathway map
Frequency of somatic alterationsTumor type
Base substitutions, insertions, and deletions
Copy number alterations
Distribution of tumor mutation burdenTMB
List of driver somatic mutations
| Genomic Coordinates (GRCh37/hg19) | Reference | Variant | Exon | Amino Acid change | Coding DNA change | COSMIC (v92) | Classification | No. of Samples |
|---|---|---|---|---|---|---|---|---|
| chrX:47426121 | C | T | 7 / 16 | p.S214F | c.641C>T | COSV51691446 | Tier1 | 1 / 52 |