Side Menu

ARID2

Basic information

Official gene symbol
AT-rich interaction domain 2
Conventional gene symbol
BAF200, CSS6, p200
Classification
Tumor suppressor gene
Official gene ID
196528(Refseq)
196528 (KEGG)
Transcript ID
NM_152641
Functional classification
Epigenetic regulation
Signaling pathway
Epigenetic modification
Chromosomal location
12q12 (chr12:46123620..46298861)
Protein length
1,835

Chromosome ideogram

Frequency of somatic alterationsTumor type

Base substitutions, insertions, and deletions

Copy number alterations

Distribution of tumor mutation burdenTMB

List of driver somatic mutations

Genomic Coordinates (GRCh37/hg19) Reference Variant Exon Amino Acid change Coding DNA change COSMIC (v92) Classification No. of Samples
chr12:46125084 C T 3 / 21 p.Q91* c.271C>T COSV57596692 Tier2 1 / 156
chr12:46211472 T G 5 / 21 p.Y146* c.438T>G   Tier2 1 / 156
chr12:46211482 ATGGACTT A 5 / 21 p.M150fs c.450_456delGGACTTT   Tier2 1 / 156
chr12:46215239 G A 6 / 21 p.W225* c.674G>A   Tier2 1 / 156
chr12:46215247 A T 6 / 21 p.K228* c.682A>T   Tier2 1 / 156
chr12:46230538 G T 8 / 21 p.E263* c.787G>T COSV100536438 Tier2 1 / 156
chr12:46230543 G A 8 / 21 p.W264* c.792G>A   Tier2 1 / 156
chr12:46230554 CTT C 8 / 21 p.L269fs c.805_806delTT COSV57613080 Tier2 1 / 156
chr12:46230649 G T 8 / 21 p.E300* c.898G>T   Tier2 1 / 156
chr12:46230711 AC A 8 / 21 p.H321fs c.961delC   Tier2 1 / 156
chr12:46230717 TCATTTTA T 8 / 21 p.H323fs c.967_973delCATTTTA   Tier2 1 / 156
chr12:46233231 CA C 11 / 21 p.A485fs c.1452delA   Tier2 1 / 156
chr12:46240680 G T 12 / 21 p.G514* c.1540G>T   Tier2 1 / 156
chr12:46242723 TA T 13 / 21 p.T563fs c.1687delA   Tier2 1 / 156
chr12:46243487 C T 14 / 21 p.Q614* c.1840C>T COSV57607839 Tier2 1 / 156
chr12:46243836 C T 15 / 21 p.Q644* c.1930C>T   Tier2 1 / 156
chr12:46243962 C T 15 / 21 p.Q686* c.2056C>T   Tier2 1 / 156
chr12:46243986 C T 15 / 21 p.Q694* c.2080C>T COSV57618014 Tier2 1 / 156
chr12:46244112 G T 15 / 21 p.G736* c.2206G>T   Tier2 1 / 156
chr12:46244127 AGTTCT A 15 / 21 p.S742fs c.2225_2229delCTGTT   Tier2 1 / 156
chr12:46244139 C T 15 / 21 p.Q745* c.2233C>T COSV100535893 Tier2 1 / 156
chr12:46244322 C T 15 / 21 p.Q806* c.2416C>T   Tier2 1 / 156
chr12:46244362 AACAGTTAATCACC A 15 / 21 p.Q820fs c.2460_2472delGTTAATCACCACA   Tier2 1 / 156
chr12:46244437 ATACTGTT A 15 / 21 p.D844fs c.2532_2538delTACTGTT   Tier2 1 / 156
chr12:46244529 G T 15 / 21 p.G875* c.2623G>T   Tier2 1 / 156
chr12:46244664 C T 15 / 21 p.Q920* c.2758C>T COSV57609194 Tier2 1 / 156
chr12:46244697 C T 15 / 21 p.Q931* c.2791C>T   Tier2 1 / 156
chr12:46244706 C T 15 / 21 p.Q934* c.2800C>T COSV57607212 Tier2 1 / 156
chr12:46244830 C A 15 / 21 p.S975* c.2924C>A   Tier2 1 / 156
chr12:46244874 TCGTCCTCTACCCCTCAATCA T 15 / 21 p.S991fs c.2970_2989delGTCCTCTACCCCTCAATCAC   Tier2 1 / 156
chr12:46244929 CTG C 15 / 21 p.V1009fs c.3026_3027delTG   Tier2 1 / 156
chr12:46244985 C CAA 15 / 21 p.V1028fs c.3080_3081dupAA   Tier2 1 / 156
chr12:46244997 C T 15 / 21 p.Q1031* c.3091C>T COSV57609049 Tier2 1 / 156
chr12:46245021 C T 15 / 21 p.Q1039* c.3115C>T COSV57617464 Tier2 1 / 156
chr12:46245076 CGA C 15 / 21 p.L1059fs c.3172_3173delAG   Tier2 1 / 156
chr12:46245192 C T 15 / 21 p.Q1096* c.3286C>T COSV57610169 Tier2 2 / 156
chr12:46245627 A T 15 / 21 p.K1241* c.3721A>T   Tier2 1 / 156
chr12:46245684 G T 15 / 21 p.E1260* c.3778G>T COSV57606696 Tier2 1 / 156
chr12:46245723 C T 15 / 21 p.R1273* c.3817C>T COSV57603720 Tier2 1 / 156
chr12:46245832 C G 15 / 21 p.S1309* c.3926C>G COSV57594609 Tier2 1 / 156
chr12:46246023 AG A 15 / 21 p.S1373fs c.4118delG   Tier2 1 / 156
chr12:46246273 T A 15 / 21 p.L1456* c.4367T>A   Tier2 1 / 156
chr12:46246514 TAGAATTGTTACAATCAGTGACCCCAACA T 15 / 21 p.R1537fs c.4610_4637delGAATTGTTACAATCAGTGACCCCAACAA   Tier2 1 / 156
chr12:46285582 C T 17 / 21 p.Q1648* c.4942C>T COSV100537088 Tier2 1 / 156
chr12:46285669 C T 17 / 21 p.R1677* c.5029C>T COSV57614810 Tier2 1 / 156
chr12:46287446 C T 20 / 21 p.R1769* c.5305C>T COSV57598720 Tier2 3 / 156
chr12:46287503 A T 20 / 21 p.R1788* c.5362A>T COSV57597812 Tier2 1 / 156