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BCL10
Basic information
- Official gene symbol
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BCL10 immune signaling adaptor
- Conventional gene symbol
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CARMEN, CIPER, CLAP, IMD37, c-E10, mE10
- Classification
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Tumor suppressor gene
- Official gene ID
- Transcript ID
- Functional classification
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Tumor growth and progression
- Signaling pathway
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NFKB
- Chromosomal location
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1p22.3 (chr1:85733310..85742035, complement)
- Protein length
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233
Chromosome ideogram
Frequency of somatic alterationsTumor type
Base substitutions, insertions, and deletions
Copy number alterations
Distribution of tumor mutation burdenTMB
List of driver somatic mutations
| Genomic Coordinates (GRCh37/hg19) | Reference | Variant | Exon | Amino Acid change | Coding DNA change | COSMIC (v92) | Classification | No. of Samples |
|---|---|---|---|---|---|---|---|---|
| chr1:85733318 | G | A | 3 / 3 | p.R232* | c.694C>T | Tier2 | 1 / 28 | |
| chr1:85733338 | A | T | 3 / 3 | p.L225* | c.674T>A | COSV65353696 | Tier2 | 1 / 28 |
| chr1:85733374 | CCTT | C | 3 / 3 | p.E212del | c.635_637delAAG | Tier1 | 1 / 28 | |
| chr1:85733480 | C | A | 3 / 3 | p.E178* | c.532G>T | Tier2 | 1 / 28 | |
| chr1:85733537 | C | A | 3 / 3 | p.E159* | c.475G>T | Tier2 | 1 / 28 |