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BCOR

Basic information

Official gene symbol
BCL6 corepressor
Conventional gene symbol
ANOP2, MAA2, MCOPS2
Classification
Tumor suppressor gene
Official gene ID
54880(Refseq)
54880 (KEGG)
Transcript ID
NM_001123385
Functional classification
Epigenetic regulation
Signaling pathway
Epigenetic modification
Chromosomal location
Xp11.4 (chrX:39911362..39937182, complement)
Protein length
1,755

Chromosome ideogram

Frequency of somatic alterationsTumor type

Base substitutions, insertions, and deletions

Copy number alterations

Distribution of tumor mutation burdenTMB

List of driver somatic mutations

Genomic Coordinates (GRCh37/hg19) Reference Variant Exon Amino Acid change Coding DNA change COSMIC (v92) Classification No. of Samples
chrX:39931632 ACTGGAATCTG A 4 / 15 p.A986fs c.2957_2966delCAGATTCCAG   Tier2 1 / 132
chrX:39931673 G A 4 / 15 p.R976* c.2926C>T COSV60709955 Tier2 1 / 132
chrX:39932057 G A 4 / 15 p.Q848* c.2542C>T   Tier2 1 / 132
chrX:39932171 G A 4 / 15 p.R810* c.2428C>T COSV60703357 Tier2 1 / 132
chrX:39932669 C A 4 / 15 p.E644* c.1930G>T COSV60717993 Tier2 1 / 132
chrX:39933009 CTTGT C 4 / 15 p.N529fs c.1586_1589delACAA   Tier2 1 / 132
chrX:39933072 C T 4 / 15 p.W509* c.1527G>A   Tier2 1 / 132
chrX:39933092 TG T 4 / 15 p.S503fs c.1506delC   Tier2 1 / 132
chrX:39933459 GCTAA G 4 / 15 p.V379fs c.1136_1139delTTAG COSV60710876 Tier2 1 / 132
chrX:39933787 GA G 4 / 15 p.S271fs c.811delT   Tier2 1 / 132
chrX:39933811 G C 4 / 15 p.S263* c.788C>G   Tier2 1 / 132
chrX:39933926 G A 4 / 15 p.Q225* c.673C>T   Tier2 1 / 132
chrX:39934045 C CT 4 / 15 p.S185fs c.553dupA   Tier2 1 / 132
chrX:39923604 G A 7 / 15 p.R1163* c.3487C>T COSV60713352 Tier2 1 / 132
chrX:39923059 G A 8 / 15 p.R1217* c.3649C>T COSV60700105 Tier2 1 / 132
chrX:39921591 G T 10 / 15 p.S1410* c.4229C>A   Tier2 1 / 132
chrX:39916427 TAC T 11 / 15 p.C1525fs c.4574_4575delGT   Tier2 1 / 132
chrX:39916463 G A 11 / 15 p.R1514* c.4540C>T COSV60703956 Tier2 3 / 132
chrX:39913515 CAG C 13 / 15 p.S1604fs c.4811_4812delCT   Tier2 1 / 132