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BMPR1A

Basic information

Official gene symbol
bone morphogenetic protein receptor type 1A
Conventional gene symbol
ACVRLK3, ALK3, CD292, SKR5
Classification
Oncogene / Tumor suppressor gene
Official gene ID
657(Refseq)
657 (KEGG)
Transcript ID
NM_004329
Functional classification
Tumor growth and progression
Signaling pathway
TGF-B
Chromosomal location
10q23.2 (chr10:88635776..88683476)
Protein length
532

Chromosome ideogram

Frequency of somatic alterationsTumor type

Base substitutions, insertions, and deletions

Copy number alterations

Distribution of tumor mutation burdenTMB

List of driver somatic mutations

Genomic Coordinates (GRCh37/hg19) Reference Variant Exon Amino Acid change Coding DNA change COSMIC (v92) Classification No. of Samples
chr10:88635817 T G 3 / 13 p.Y14* c.42T>G   Tier2 1 / 46
chr10:88651930 G T 5 / 13 p.E93* c.277G>T   Tier2 1 / 46
chr10:88672046 G T 8 / 13 p.E194* c.580G>T   Tier2 1 / 46
chr10:88678957 AGGTTCCT A 10 / 13 p.S301fs c.900_906delTTCCTGG   Tier2 1 / 46
chr10:88678970 C T 10 / 13 p.Q304* c.910C>T   Tier2 1 / 46
chr10:88683357 C T 13 / 13 p.R494* c.1480C>T COSV64404915 Tier2 1 / 46