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CBFB
Basic information
- Official gene symbol
-
core-binding factor subunit beta
- Conventional gene symbol
-
PEBP2B
- Classification
-
Tumor suppressor gene
- Official gene ID
- Transcript ID
- Functional classification
-
Transcriptional regulation
- Signaling pathway
-
Transcriptional regulation
- Chromosomal location
-
16q22.1 (chr16:67063311..67132635)
- Protein length
-
182
Chromosome ideogram
Frequency of somatic alterationsTumor type
Base substitutions, insertions, and deletions
Copy number alterations
Distribution of tumor mutation burdenTMB
List of driver somatic mutations
| Genomic Coordinates (GRCh37/hg19) | Reference | Variant | Exon | Amino Acid change | Coding DNA change | COSMIC (v92) | Classification | No. of Samples |
|---|---|---|---|---|---|---|---|---|
| chr16:67063684 | C | T | 2 / 6 | p.Q45* | c.133C>T | COSV51999364 | Tier2 | 1 / 32 |
| chr16:67070557 | G | T | 3 / 6 | p.G61* | c.181G>T | Tier2 | 1 / 32 | |
| chr16:67070644 | A | ACT | 3 / 6 | p.R90fs | c.268_269insCT | Tier2 | 1 / 32 | |
| chr16:67100610 | TG | T | 4 / 6 | p.N104fs | c.309delG | Tier2 | 1 / 32 |