CDC73

Basic information

Official gene symbol: cell division cycle 73
Conventional gene symbol: C1orf28, FIHP, HPTJT, HRPT1, HRPT2, HYX
Classification: Tumor suppressor gene
Official gene ID: 79577(Refseq)

79577 (KEGG)
Transcript ID: NM_024529

Functional classification: Transcriptional regulation
Signaling pathway: Transcriptional regulation
Chromosomal location: 1q31.2 (chr1:193091331..193219842)
Protein length: 531

Chromosome ideogram

Frequency of somatic alterationsTumor type

Base substitutions, insertions, and deletions

Copy number alterations

Distribution of tumor mutation burdenTMB

List of driver somatic mutations

Genomic Coordinates (GRCh37/hg19)	Reference	Variant	Exon	Amino Acid change	Coding DNA change	COSMIC (v92)	Classification	No. of Samples
chr1:193091368	TC	T	1 / 17	p.Q14fs	c.40delC	COSV66465783	Tier2	1 / 53
chr1:193104684	G	T	5 / 17	p.E130*	c.388G>T		Tier2	1 / 53
chr1:193104711	C	T	5 / 17	p.R139*	c.415C>T	COSV66465843	Tier2	1 / 53
chr1:193111145	C	CAG	7 / 17	p.V230fs	c.687_688dupAG	COSV66467169	Tier2	1 / 53
chr1:193117069	C	T	8 / 17	p.R268*	c.802C>T		Tier2	1 / 53
chr1:193119506	A	T	9 / 17	p.K301*	c.901A>T		Tier2	1 / 53