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CYLD
Basic information
- Official gene symbol
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CYLD lysine 63 deubiquitinase
- Conventional gene symbol
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BRSS, CDMT, CYLD1, CYLDI, EAC, MFT, MFT1, SBS, TEM, USPL2
- Classification
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Tumor suppressor gene
- Official gene ID
- Transcript ID
- Functional classification
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Protein homeostasis
- Signaling pathway
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Protein homeostasis
- Chromosomal location
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16q12.1 (chr16:50783610..50830419)
- Protein length
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956
Chromosome ideogram
Frequency of somatic alterationsTumor type
Base substitutions, insertions, and deletions
Copy number alterations
Distribution of tumor mutation burdenTMB
List of driver somatic mutations
| Genomic Coordinates (GRCh37/hg19) | Reference | Variant | Exon | Amino Acid change | Coding DNA change | COSMIC (v92) | Classification | No. of Samples |
|---|---|---|---|---|---|---|---|---|
| chr16:50785743 | G | T | 5 / 20 | p.E245* | c.733G>T | COSV61093800 | Tier2 | 1 / 54 |
| chr16:50830275 | C | A | 20 / 20 | p.C909* | c.2727C>A | Tier2 | 1 / 54 |