Side Menu
EPHA3
Basic information
- Official gene symbol
-
EPH receptor A3
- Conventional gene symbol
-
EK4, ETK, ETK1, HEK, HEK4, TYRO4
- Classification
-
Tumor suppressor gene
- Official gene ID
- Transcript ID
- Functional classification
-
Tumor growth and progression
- Signaling pathway
-
RTK
- Chromosomal location
-
3p11.1 (chr3:89156899..89528652)
- Protein length
-
983
Chromosome ideogram
Pathway map
Frequency of somatic alterationsTumor type
Base substitutions, insertions, and deletions
Copy number alterations
Distribution of tumor mutation burdenTMB
List of driver somatic mutations
| Genomic Coordinates (GRCh37/hg19) | Reference | Variant | Exon | Amino Acid change | Coding DNA change | COSMIC (v92) | Classification | No. of Samples |
|---|---|---|---|---|---|---|---|---|
| chr3:89156971 | C | T | 1 / 17 | p.Q25* | c.73C>T | Tier2 | 1 / 165 | |
| chr3:89259099 | G | A | 3 / 17 | p.W81* | c.243G>A | Tier2 | 1 / 165 | |
| chr3:89480345 | C | T | 13 / 17 | p.R728* | c.2182C>T | COSV60696980 | Tier2 | 1 / 165 |