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ERRFI1

Basic information

Official gene symbol
ERBB receptor feedback inhibitor 1
Conventional gene symbol
GENE-33, MIG-6, MIG6, RALT
Classification
Tumor suppressor gene
Official gene ID
54206(Refseq)
54206 (KEGG)
Transcript ID
NM_018948
Functional classification
Tumor growth and progression
Signaling pathway
RTK
Chromosomal location
1p36.23 (chr1:8073270..8075679, complement)
Protein length
462

Chromosome ideogram

Frequency of somatic alterationsTumor type

Base substitutions, insertions, and deletions

Copy number alterations

Distribution of tumor mutation burdenTMB

List of driver somatic mutations

Genomic Coordinates (GRCh37/hg19) Reference Variant Exon Amino Acid change Coding DNA change COSMIC (v92) Classification No. of Samples
chr1:8073461 G A 4 / 4 p.R400* c.1198C>T   Tier2 1 / 37
chr1:8073476 AAT A 4 / 4 p.Y394fs c.1181_1182delAT   Tier2 1 / 37
chr1:8073681 T TG 4 / 4 p.P327fs c.977dupC   Tier2 1 / 37
chr1:8073911 GA G 4 / 4 p.H250fs c.747delT   Tier2 1 / 37
chr1:8073929 G A 4 / 4 p.R244* c.730C>T   Tier2 1 / 37
chr1:8074064 G A 4 / 4 p.R199* c.595C>T   Tier2 1 / 37
chr1:8074140 GAATTCCAC G 4 / 4 p.V171fs c.511_518delGTGGAATT   Tier2 1 / 37
chr1:8074157 CTG C 4 / 4 p.T167fs c.500_501delCA COSV66311608 Tier2 1 / 37
chr1:8074265 G GT 4 / 4 p.P132fs c.393dupA   Tier2 1 / 37