Side Menu
FANCA
Basic information
- Official gene symbol
-
FA complementation group A
- Conventional gene symbol
-
FA, FA-H, FA1, FAA, FACA, FAH, FANCH
- Classification
-
Tumor suppressor gene
- Official gene ID
- Transcript ID
- Functional classification
-
Genome maintenance
- Signaling pathway
-
Core DNA Damage Response
- Chromosomal location
-
16q24.3 (chr16:89805009..89883023, complement)
- Protein length
-
1,455
Chromosome ideogram
Frequency of somatic alterationsTumor type
Base substitutions, insertions, and deletions
Copy number alterations
Distribution of tumor mutation burdenTMB
List of driver somatic mutations
| Genomic Coordinates (GRCh37/hg19) | Reference | Variant | Exon | Amino Acid change | Coding DNA change | COSMIC (v92) | Classification | No. of Samples |
|---|---|---|---|---|---|---|---|---|
| chr16:89877132 | C | A | 5 / 43 | p.E169* | c.505G>T | COSV66884833 | Tier2 | 1 / 91 |
| chr16:89838138 | G | C | 23 / 43 | p.S700* | c.2099C>G | COSV101225325 | Tier2 | 1 / 91 |