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FGFR3
Basic information
- Official gene symbol
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fibroblast growth factor receptor 3
- Conventional gene symbol
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ACH, CD333, CEK2, HSFGFR3EX, JTK4
- Classification
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Oncogene
- Official gene ID
- Transcript ID
- Functional classification
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Tumor growth and progression
- Signaling pathway
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RTK
- Chromosomal location
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4p16.3 (chr4:1795662..1808989)
- Protein length
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806
Chromosome ideogram
Pathway map
Frequency of somatic alterationsTumor type
Base substitutions, insertions, and deletions
Copy number alterations
Distribution of tumor mutation burdenTMB
List of driver somatic mutations
| Genomic Coordinates (GRCh37/hg19) | Reference | Variant | Exon | Amino Acid change | Coding DNA change | COSMIC (v92) | Classification | No. of Samples |
|---|---|---|---|---|---|---|---|---|
| chr4:1803564 | C | T | 7 / 18 | p.R248C | c.742C>T | COSV53390662 | Tier1 | 2 / 69 |
| chr4:1803568 | C | G | 7 / 18 | p.S249C | c.746C>G | COSV53390026 | Tier1 | 1 / 69 |
| chr4:1806099 | A | G | 9 / 18 | p.Y373C | c.1118A>G | COSV53390174 | Tier1 | 1 / 69 |