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FLCN
Basic information
- Official gene symbol
-
folliculin
- Conventional gene symbol
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BHD, DENND8B, FLCL
- Classification
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Tumor suppressor gene
- Official gene ID
- Transcript ID
- Functional classification
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Tumor growth and progression
- Signaling pathway
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PI3K/Akt/mTOR
- Chromosomal location
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17p11.2 (chr17:17116969..17131451, complement)
- Protein length
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579
Chromosome ideogram
Pathway map
Frequency of somatic alterationsTumor type
Base substitutions, insertions, and deletions
Copy number alterations
Distribution of tumor mutation burdenTMB
List of driver somatic mutations
| Genomic Coordinates (GRCh37/hg19) | Reference | Variant | Exon | Amino Acid change | Coding DNA change | COSMIC (v92) | Classification | No. of Samples |
|---|---|---|---|---|---|---|---|---|
| chr17:17118502 | G | A | 12 / 14 | p.R477* | c.1429C>T | COSV53263420 | Tier2 | 1 / 41 |
| chr17:17118567 | TCA | T | 12 / 14 | p.C454fs | c.1362_1363delTG | Tier2 | 1 / 41 |