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GNAS
Basic information
- Official gene symbol
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GNAS complex locus
- Conventional gene symbol
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AHO, C20orf45, GNAS1, GPSA, GSA, GSP, NESP, PITA3, POH, SCG6, SgVI
- Classification
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Oncogene
- Official gene ID
- Transcript ID
- Functional classification
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Tumor growth and progression
- Signaling pathway
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GPCR
- Chromosomal location
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20q13.32 (chr20:57428321..57485884)
- Protein length
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1,037
Chromosome ideogram
Frequency of somatic alterationsTumor type
Base substitutions, insertions, and deletions
Copy number alterations
Distribution of tumor mutation burdenTMB
List of driver somatic mutations
| Genomic Coordinates (GRCh37/hg19) | Reference | Variant | Exon | Amino Acid change | Coding DNA change | COSMIC (v92) | Classification | No. of Samples |
|---|---|---|---|---|---|---|---|---|
| chr20:57484420 | C | T | 8 / 13 | p.R844C | c.2530C>T | COSV55670339 | Tier1 | 14 / 190 |
| chr20:57484421 | G | A | 8 / 13 | p.R844H | c.2531G>A | COSV55670349 | Tier1 | 16 / 190 |