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HOXB13

Basic information

Official gene symbol
homeobox B13
Conventional gene symbol
HPC9, PSGD
Classification
Oncogene / Tumor suppressor gene
Official gene ID
10481(Refseq)
10481 (KEGG)
Transcript ID
NM_006361
Functional classification
Transcriptional regulation
Signaling pathway
Transcriptional regulation
Chromosomal location
17q21.32 (chr17:46804152..46805955, complement)
Protein length
284

Chromosome ideogram

Frequency of somatic alterationsTumor type

Base substitutions, insertions, and deletions

Copy number alterations

Distribution of tumor mutation burdenTMB

List of driver somatic mutations

Genomic Coordinates (GRCh37/hg19) Reference Variant Exon Amino Acid change Coding DNA change COSMIC (v92) Classification No. of Samples
chr17:46805459 AC A 1 / 2 p.V166fs c.496delG   Tier2 1 / 38
chr17:46805463 G GC 1 / 2 p.P165fs c.492dupG   Tier2 1 / 38
chr17:46805475 CAT C 1 / 2 p.H160fs c.479_480delAT   Tier2 1 / 38
chr17:46805481 G A 1 / 2 p.R159* c.475C>T   Tier2 1 / 38
chr17:46805789 G T 1 / 2 p.S56* c.167C>A   Tier2 1 / 38
chr17:46804239 C CA 2 / 2 p.E257fs c.767_768insT   Tier2 1 / 38
chr17:46804313 C A 2 / 2 p.E232* c.694G>T   Tier2 1 / 38