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IDH1
Basic information
- Official gene symbol
-
isocitrate dehydrogenase (NADP(+)) 1
- Conventional gene symbol
-
HEL-216, HEL-S-26, IDCD, IDPC, PICD
- Classification
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Oncogene
- Official gene ID
- Transcript ID
- Functional classification
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Epigenetic regulation
- Signaling pathway
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Epigenetic modification
- Chromosomal location
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2q34 (chr2:209101803..209116275, complement)
- Protein length
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414
Chromosome ideogram
Frequency of somatic alterationsTumor type
Base substitutions, insertions, and deletions
Copy number alterations
Distribution of tumor mutation burdenTMB
List of driver somatic mutations
| Genomic Coordinates (GRCh37/hg19) | Reference | Variant | Exon | Amino Acid change | Coding DNA change | COSMIC (v92) | Classification | No. of Samples |
|---|---|---|---|---|---|---|---|---|
| chr2:209113112 | C | T | 4 / 10 | p.R132H | c.395G>A | COSV61615239 | Tier1 | 30 / 70 |
| chr2:209113113 | G | A | 4 / 10 | p.R132C | c.394C>T | COSV61615256 | Tier1 | 13 / 70 |
| chr2:209113113 | G | T | 4 / 10 | p.R132S | c.394C>A | COSV61615649 | Tier1 | 1 / 70 |