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JAK3
Basic information
- Official gene symbol
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Janus kinase 3
- Conventional gene symbol
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JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
- Classification
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Oncogene
- Official gene ID
- Transcript ID
- Functional classification
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Tumor growth and progression
- Signaling pathway
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JAK/STAT
- Chromosomal location
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19p13.11 (chr19:17937552..17955226, complement)
- Protein length
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1,124
Chromosome ideogram
Frequency of somatic alterationsTumor type
Base substitutions, insertions, and deletions
Copy number alterations
Distribution of tumor mutation burdenTMB
List of driver somatic mutations
| Genomic Coordinates (GRCh37/hg19) | Reference | Variant | Exon | Amino Acid change | Coding DNA change | COSMIC (v92) | Classification | No. of Samples |
|---|---|---|---|---|---|---|---|---|
| chr19:17945969 | C | T | 15 / 24 | p.R657Q | c.1970G>A | COSV71685371 | Tier1 | 1 / 100 |