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MAP2K2
Basic information
- Official gene symbol
-
mitogen-activated protein kinase kinase 2
- Conventional gene symbol
-
CFC4, MAPKK2, MEK2, MKK2, PRKMK2
- Classification
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Oncogene
- Official gene ID
- Transcript ID
- Functional classification
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Tumor growth and progression
- Signaling pathway
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MAPK
- Chromosomal location
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19p13.3 (chr19:4090596..4123872, complement)
- Protein length
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400
Chromosome ideogram
Pathway map
Frequency of somatic alterationsTumor type
Base substitutions, insertions, and deletions
Copy number alterations
Distribution of tumor mutation burdenTMB
List of driver somatic mutations
| Genomic Coordinates (GRCh37/hg19) | Reference | Variant | Exon | Amino Acid change | Coding DNA change | COSMIC (v92) | Classification | No. of Samples |
|---|---|---|---|---|---|---|---|---|
| chr19:4117541 | T | G | 2 / 11 | p.Q60P | c.179A>C | COSV53562028 | Tier2 | 1 / 57 |
| chr19:4101103 | C | T | 6 / 11 | p.E207K | c.619G>A | COSV53562848 | Tier1 | 1 / 57 |