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MAPK1

Basic information

Official gene symbol
mitogen-activated protein kinase 1
Conventional gene symbol
ERK, ERK-2, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p41, p41mapk, p42-MAPK
Classification
Oncogene
Official gene ID
5594(Refseq)
5594 (KEGG)
Transcript ID
NM_002745
Functional classification
Tumor growth and progression
Signaling pathway
MAPK
Chromosomal location
22q11.22 (chr22:22123493..22221730, complement)
Protein length
360

Chromosome ideogram

Pathway map

Frequency of somatic alterationsTumor type

Base substitutions, insertions, and deletions

Copy number alterations

Distribution of tumor mutation burdenTMB

List of driver somatic mutations

Genomic Coordinates (GRCh37/hg19) Reference Variant Exon Amino Acid change Coding DNA change COSMIC (v92) Classification No. of Samples
chr22:22127164 C T 7 / 9 p.E322K c.964G>A COSV53184855 Tier2 3 / 28