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NFKBIA
Basic information
- Official gene symbol
-
NFKB inhibitor alpha
- Conventional gene symbol
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EDAID2, IKBA, MAD-3, NFKBI
- Classification
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Tumor suppressor gene
- Official gene ID
- Transcript ID
- Functional classification
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Tumor growth and progression
- Signaling pathway
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NFKB
- Chromosomal location
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14q13.2 (chr14:35871219..35873850, complement)
- Protein length
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317
Chromosome ideogram
Frequency of somatic alterationsTumor type
Base substitutions, insertions, and deletions
Copy number alterations
Distribution of tumor mutation burdenTMB
List of driver somatic mutations
| Genomic Coordinates (GRCh37/hg19) | Reference | Variant | Exon | Amino Acid change | Coding DNA change | COSMIC (v92) | Classification | No. of Samples |
|---|---|---|---|---|---|---|---|---|
| chr14:35872386 | G | GGA | 3 / 6 | p.H173fs | c.515_516dupTC | Tier2 | 1 / 29 | |
| chr14:35871629 | ACT | A | 5 / 6 | p.E292fs | c.875_876delAG | Tier2 | 1 / 29 | |
| chr14:35871632 | CTG | C | 5 / 6 | p.T291fs | c.872_873delCA | COSV53752303 | Tier2 | 1 / 29 |