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NPM1
Basic information
- Official gene symbol
-
nucleophosmin 1
- Conventional gene symbol
-
B23, NPM
- Classification
-
Oncogene / Tumor suppressor gene
- Official gene ID
- Transcript ID
- Functional classification
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Epigenetic regulation
- Signaling pathway
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Epigenetic modification
- Chromosomal location
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5q35.1 (chr5:170814953..170837569)
- Protein length
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294
Chromosome ideogram
Frequency of somatic alterationsTumor type
Base substitutions, insertions, and deletions
Copy number alterations
Distribution of tumor mutation burdenTMB
List of driver somatic mutations
| Genomic Coordinates (GRCh37/hg19) | Reference | Variant | Exon | Amino Acid change | Coding DNA change | COSMIC (v92) | Classification | No. of Samples |
|---|---|---|---|---|---|---|---|---|
| chr5:170832312 | G | T | 9 / 11 | p.E226* | c.676G>T | Tier2 | 1 / 13 |