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PPP6C
Basic information
- Official gene symbol
-
protein phosphatase 6 catalytic subunit
- Conventional gene symbol
-
PP6, PP6C
- Classification
-
Tumor suppressor gene
- Official gene ID
- Transcript ID
- Functional classification
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Epigenetic regulation
- Signaling pathway
-
Epigenetic modification
- Chromosomal location
-
9q33.3 (chr9:127911952..127951997, complement)
- Protein length
-
305
Chromosome ideogram
Frequency of somatic alterationsTumor type
Base substitutions, insertions, and deletions
Copy number alterations
Distribution of tumor mutation burdenTMB
List of driver somatic mutations
| Genomic Coordinates (GRCh37/hg19) | Reference | Variant | Exon | Amino Acid change | Coding DNA change | COSMIC (v92) | Classification | No. of Samples |
|---|---|---|---|---|---|---|---|---|
| chr9:127920568 | G | A | 4 / 7 | p.R111* | c.331C>T | COSV65208029 | Tier2 | 1 / 30 |
| chr9:127915853 | G | A | 6 / 7 | p.R210* | c.628C>T | Tier2 | 1 / 30 | |
| chr9:127912080 | G | A | 7 / 7 | p.R264C | c.790C>T | COSV65207035 | Tier2 | 2 / 30 |