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TNFAIP3
Basic information
- Official gene symbol
-
TNF alpha induced protein 3
- Conventional gene symbol
-
A20, AISBL, OTUD7C, TNFA1P2
- Classification
-
Tumor suppressor gene
- Official gene ID
- Transcript ID
- Functional classification
-
Tumor growth and progression
- Signaling pathway
-
NFKB
- Chromosomal location
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6q23.3 (chr6:138192365..138202456)
- Protein length
-
790
Chromosome ideogram
Frequency of somatic alterationsTumor type
Base substitutions, insertions, and deletions
Copy number alterations
Distribution of tumor mutation burdenTMB
List of driver somatic mutations
| Genomic Coordinates (GRCh37/hg19) | Reference | Variant | Exon | Amino Acid change | Coding DNA change | COSMIC (v92) | Classification | No. of Samples |
|---|---|---|---|---|---|---|---|---|
| chr6:138199594 | G | T | 7 / 9 | p.E338* | c.1012G>T | COSV52801868 | Tier2 | 1 / 64 |
| chr6:138200158 | C | T | 7 / 9 | p.Q526* | c.1576C>T | Tier2 | 1 / 64 | |
| chr6:138200470 | G | T | 7 / 9 | p.E630* | c.1888G>T | Tier2 | 1 / 64 | |
| chr6:138201229 | AAGTC | A | 8 / 9 | p.S645fs | c.1933_1936delAGTC | Tier2 | 1 / 64 |