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TP63

Basic information

Official gene symbol
tumor protein p63
Conventional gene symbol
B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p51, p53CP, p63, p73H, p73L
Classification
Oncogene / Tumor suppressor gene
Official gene ID
8626(Refseq)
8626 (KEGG)
Transcript ID
NM_003722
Functional classification
Transcriptional regulation
Signaling pathway
Transcriptional regulation
Chromosomal location
3q28 (chr3:189349305..189612291)
Protein length
680

Chromosome ideogram

Frequency of somatic alterationsTumor type

Base substitutions, insertions, and deletions

Copy number alterations

Distribution of tumor mutation burdenTMB

List of driver somatic mutations

Genomic Coordinates (GRCh37/hg19) Reference Variant Exon Amino Acid change Coding DNA change COSMIC (v92) Classification No. of Samples
chr3:189455575 C T 2 / 14 p.R37* c.109C>T COSV53221904(SNP) Tier2 2 / 83
chr3:189582050 C A 5 / 14 p.C203* c.609C>A   Tier2 1 / 83
chr3:189584506 G T 6 / 14 p.E268* c.802G>T   Tier2 1 / 83
chr3:189586442 G T 8 / 14 p.E356* c.1066G>T   Tier2 1 / 83
chr3:189590753 C T 10 / 14 p.Q440* c.1318C>T   Tier2 1 / 83
chr3:189608604 C A 13 / 14 p.S560* c.1679C>A   Tier2 1 / 83
chr3:189608654 G T 13 / 14 p.E577* c.1729G>T   Tier2 1 / 83
chr3:189612028 C T 14 / 14 p.R594* c.1780C>T COSV53196111 Tier2 3 / 83