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U2AF1
Basic information
- Official gene symbol
-
U2 small nuclear RNA auxiliary factor 1
- Conventional gene symbol
-
FP793, RN, RNU2AF1, U2AF35, U2AFBP
- Classification
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Oncogene
- Official gene ID
- Transcript ID
- Functional classification
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Transcriptional regulation
- Signaling pathway
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RNA metabolism
- Chromosomal location
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21q22.3 (chr21:44513212..44527604, complement)
- Protein length
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240
Chromosome ideogram
Frequency of somatic alterationsTumor type
Base substitutions, insertions, and deletions
Copy number alterations
Distribution of tumor mutation burdenTMB
List of driver somatic mutations
| Genomic Coordinates (GRCh37/hg19) | Reference | Variant | Exon | Amino Acid change | Coding DNA change | COSMIC (v92) | Classification | No. of Samples |
|---|---|---|---|---|---|---|---|---|
| chr21:44524456 | G | A | 2 / 8 | p.S34F | c.101C>T | COSV52341059 | Tier2 | 9 / 35 |
| chr21:44524456 | G | T | 2 / 8 | p.S34Y | c.101C>A | COSV52341472 | Tier1 | 2 / 35 |
| chr21:44524486 | A | G | 2 / 8 | p.I24T | c.71T>C | COSV52341721 | Tier2 | 1 / 35 |