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WT1
Basic information
- Official gene symbol
-
WT1 transcription factor
- Conventional gene symbol
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AWT1, GUD, NPHS4, WAGR, WIT-2, WT33
- Classification
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Oncogene / Tumor suppressor gene
- Official gene ID
- Transcript ID
- Functional classification
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Transcriptional regulation
- Signaling pathway
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Transcriptional regulation
- Chromosomal location
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11p13 (chr11:32410604..32456906, complement)
- Protein length
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522
Chromosome ideogram
Frequency of somatic alterationsTumor type
Base substitutions, insertions, and deletions
Copy number alterations
Distribution of tumor mutation burdenTMB
List of driver somatic mutations
| Genomic Coordinates (GRCh37/hg19) | Reference | Variant | Exon | Amino Acid change | Coding DNA change | COSMIC (v92) | Classification | No. of Samples |
|---|---|---|---|---|---|---|---|---|
| chr11:32414242 | G | A | 8 / 10 | p.Q437* | c.1309C>T | COSV60071956 | Tier2 | 1 / 82 |
| chr11:32413578 | G | A | 9 / 10 | p.R458* | c.1372C>T | COSV60066326 | Tier2 | 1 / 82 |