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XRCC2
Basic information
- Official gene symbol
-
X-ray repair cross complementing 2
- Conventional gene symbol
-
FANCU
- Classification
-
Tumor suppressor gene
- Official gene ID
- Transcript ID
- Functional classification
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Genome maintenance
- Signaling pathway
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Core DNA Damage Response
- Chromosomal location
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7q36.1 (chr7:152345727..152373164, complement)
- Protein length
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280
Chromosome ideogram
Pathway map
Frequency of somatic alterationsTumor type
Base substitutions, insertions, and deletions
Copy number alterations
Distribution of tumor mutation burdenTMB
List of driver somatic mutations
| Genomic Coordinates (GRCh37/hg19) | Reference | Variant | Exon | Amino Acid change | Coding DNA change | COSMIC (v92) | Classification | No. of Samples |
|---|---|---|---|---|---|---|---|---|
| chr7:152357831 | C | A | 2 / 3 | p.E26* | c.76G>T | COSV100831629 | Tier2 | 1 / 22 |
| chr7:152345750 | C | A | 3 / 3 | p.E274* | c.820G>T | Tier2 | 1 / 22 | |
| chr7:152346274 | CTG | C | 3 / 3 | p.H98fs | c.294_295delCA | Tier2 | 1 / 22 |